SCHEMBL11548665

SCHEMBL11548665

CCOP(=O)(Cc1ccc(-c2nnc(-c3ccccc3)o2)cc1)OCC

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 11/20 0.56
NPC1 O15118 10/20 0.56
SMN1; SMN2 Q16637 6/20 0.56
HPGD P15428 6/20 0.56
KDM4E B2RXH2 5/20 0.56
ALDH1A1 P00352 5/20 0.56
TP53 P04637 2/20 0.56
HSD17B10 Q99714 4/20 0.49
MAPT P10636 3/20 0.49
POLB P06746 1/20 0.49
NFKB1 P19838 1/20 0.49
NFKB2 Q00653 1/20 0.49
RELA Q04206 1/20 0.49
TSHR P16473 1/20 0.48
NPY5R Q15761 1/20 0.46
GAA P10253 1/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11278523 0.87 RAB9A (0.51) RAB9ANPC1SMN1; SMN2HPGDKDM4E
SCHEMBL3109529 0.86 NPY5R (0.49) MAPTPOLBTSHRNPY5RGAA
SCHEMBL13321999 0.85 KDM4E (0.40) RAB9ANPC1SMN1; SMN2HPGDKDM4E
SCHEMBL10247666 0.84 SMN1; SMN2 (0.57) RAB9ANPC1SMN1; SMN2HPGDKDM4E
SCHEMBL29572556 0.81 HDAC6 (0.42) RAB9ANPC1SMN1; SMN2HPGDKDM4E
SCHEMBL11381710 0.81 UTRN (0.52) RAB9ANPC1SMN1; SMN2HPGDKDM4E
SCHEMBL11336027 0.80 NPC1 (0.56) RAB9ANPC1SMN1; SMN2HPGDKDM4E
SCHEMBL366215 0.79 NPY5R (0.50) HPGDMAPTPOLBTSHRNPY5R
SCHEMBL2493713 0.79 TSHR (0.44) MAPTPOLBTSHRNPY5R
SCHEMBL14401333 0.78 MEN1 (0.47) HPGDKDM4EALDH1A1MAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4138552-A 4-(V-triazolyl)-styryl optical brighteners CIBA-GEIGY CORPORATION (US) 1979-02-06 US disclosed