Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21759058 | 0.85 | POLB (0.59) | ALDH1A1TSHRPOLBCYP1A2KDM4E | |
| SCHEMBL11546336 | 0.84 | ABCB1 (0.45) | ALDH1A1TSHRPOLBCYP1A2MAPT | |
| SCHEMBL11546634 | 0.84 | POLB (0.44) | ALDH1A1TSHRPOLBCYP1A2KDM4E | |
| SCHEMBL11548610 | 0.79 | POLB (0.47) | ALDH1A1TSHRPOLBCYP1A2KDM4E | |
| SCHEMBL11548674 | 0.78 | KDM4E (0.46) | ALDH1A1CYP1A2KDM4EMAPTMAPK1 | |
| SCHEMBL16976477 | 0.76 | POLB (0.55) | ALDH1A1TSHRPOLBCYP1A2MAPT | |
| SCHEMBL11548630 | 0.75 | SMN1; SMN2 (0.43) | ALDH1A1TSHRCYP1A2KDM4EMAPT | |
| SCHEMBL11552589 | 0.75 | ALDH1A1 (0.54) | ALDH1A1TSHRPOLBCYP1A2MAPT | |
| Hydrochloric Acid SCHEMBL11548608 | 0.74 | ALDH1A1 (0.56) | ALDH1A1TSHRPOLBCYP1A2MAPT | |
| SCHEMBL11549384 | 0.74 | POLB (0.47) | ALDH1A1TSHRPOLBCYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4139623-A | HYPOTENSIVE AGENTS | C-G CORP. (US) | 1979-02-13 | — | — | US | disclosed |
| US-4027027-A | BETA-RECEPTOR-BLOCKERS, HYPOTENSIVES AND VALODILATORS; FOR TREATING ARRYTHMIAS AND ANGINA PECTORIS | CIBA-GEIGY CORPORATION (US) | 1977-05-31 | — | — | US | disclosed |