Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PRKDC | P78527 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11548553 | 0.95 | ALDH1A1 (0.51) | TDP1ALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL11548343 | 0.89 | TDP1 (0.49) | TDP1ALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL6815710 | 0.87 | HTT (0.58) | TDP1ALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL4799531 | 0.87 | HTT (0.58) | TDP1ALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL11581876 | 0.85 | MAPT (0.49) | ALDH1A1MAPTLMNAMAPK1PRSS1 | |
| SCHEMBL11596026 | 0.84 | ALDH1A1 (0.48) | TDP1ALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL10940683 | 0.84 | MAPT (0.52) | ALDH1A1MAPTLMNAMAPK1PRSS1 | |
| SCHEMBL13832435 | 0.81 | KDM4E (0.52) | TDP1ALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL11555366 | 0.81 | HTT (0.55) | TDP1ALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL6375580 | 0.81 | HTT (0.55) | TDP1ALDH1A1MAPTLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169091-A | Symmetrical and asymmetrical disazo compounds containing a bis-(nitro-aryloxy)alkane middle component | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-09-25 | — | — | US | disclosed |