Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | PRKDC | P78527 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | G6PD | P11413 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11555366 | 0.92 | HTT (0.55) | HTTTDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL3480822 | 0.92 | ALDH1A1 (0.58) | HTTTDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL6815710 | 0.90 | HTT (0.58) | HTTTDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL4799531 | 0.90 | HTT (0.58) | HTTTDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL8009996 | 0.90 | HTT (0.58) | HTTTDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL6370055 | 0.87 | ALDH1A1 (0.57) | HTTTDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL517401 | 0.87 | HTT (0.50) | HTTTDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL29785411 | 0.87 | HTT (0.50) | HTTTDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL5330357 | 0.87 | HTT (0.50) | HTTTDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL6376231 | 0.86 | HTT (0.58) | HTTTDP1ALDH1A1MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1156047-B1 | 6-SUBSTITUTED-7- HETEROQUINOXALINE CARBOXYLIC ACID DERIVATIVES AND ADDITION SALTS THEREOF AND PROCESSES FOR THE PREPARATION OF BOTH | KYORIN SEIYAKU KK (JP) | 2005-08-31 | — | — | EP | disclosed |
| US-6632813-B1 | 6-subtituted-7-heteroquinoxalinecarboxylic acid derivatives and addition salts thereof and processes for the preparation of both | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2003-10-14 | — | — | US | disclosed |
| EP-1156047-A1 | 6-SUBSTITUTED-7- HETEROQUINOXALINE CARBOXYLIC ACID DERIVATIVES AND ADDITION SALTS THEREOF AND PROCESSES FOR THE PREPARATION OF BOTH | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2001-11-21 | — | — | EP | disclosed |
| EP-0280156-B1 | PROCESS FOR THE PREPARATION OF ACETOACETYLARYLAMIDES-HETEROARYLAMIDES RESPECTIVELY OF DEACTIVED AROMATIC COMPOUNDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-11-11 | — | — | EP | disclosed |
| EP-0280156-A2 | Process for the preparation of acetoacetylarylamides-heteroarylamides respectively of deactived aromatic compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-31 | — | — | EP | disclosed |
| US-4316861-A | N-Nitroaryl-N-halosulfonyl ureas | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-02-23 | — | — | US | disclosed |
| US-4007221-A | Manufacture of nuclear-iodinated iodine compounds of aromatic character | BASF AKTIENGESELLSCHAFT (DT) | 1977-02-08 | — | — | US | disclosed |