Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11551942 | 0.85 | PGR (0.46) | PGRKCNH2ESR2ALOX5TAAR1 | |
| SCHEMBL11554460 | 0.83 | MAPT (0.51) | KCNH2ALOX5MEN1RECQLKMT2A | |
| SCHEMBL1477501 | 0.82 | KCNH2 (0.50) | PGRKCNH2MEN1RECQLKMT2A | |
| SCHEMBL11549060 | 0.81 | ASIC3 (0.42) | KCNH2MEN1KMT2AASIC3MAPT | |
| SCHEMBL11548872 | 0.81 | ESR2 (0.50) | ESR2TAAR1ASIC3FFAR1 | |
| SCHEMBL11549280 | 0.80 | PGR (0.46) | PGRKCNH2ESR2ALOX5TAAR1 | |
| SCHEMBL17616893 | 0.79 | ASIC3 (0.43) | KMT2AASIC3MAPTSMN1; SMN2 | |
| SCHEMBL11549951 | 0.78 | HAO1 (0.43) | PGRMEN1RECQLKMT2AASIC3 | |
| SCHEMBL11217017 | 0.77 | MAPT (0.55) | KCNH2MEN1RECQLKMT2AASIC3 | |
| SCHEMBL12391039 | 0.75 | ASIC3 (0.50) | KMT2AASIC3MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151294-A | Alkynols and process for their preparation | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-04-24 | — | — | US | disclosed |