Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MPI | P34949 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 3/20 | 0.48 |
| ▸ | THRA | P10827 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11552125 | 0.89 | ALDH1A1 (0.52) | ALDH1A1NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL11551512 | 0.88 | KDM4E (0.54) | ALDH1A1NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL11555272 | 0.86 | TSHR (0.61) | ALDH1A1NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL11551105 | 0.84 | KDM4E (0.59) | ALDH1A1NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL11748405 | 0.83 | MAOB (0.52) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL11554538 | 0.83 | HRH3 (0.65) | ALDH1A1NPC1RAB9ATP53SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11551776 | 0.82 | ALDH1A1 (0.50) | ALDH1A1NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL11797482 | 0.82 | ALDH1A1 (0.71) | ALDH1A1NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL11678069 | 0.81 | ALDH1A1 (0.67) | ALDH1A1NPC1RAB9ATP53SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11838528 | 0.80 | ALDH1A1 (0.59) | ALDH1A1NPC1RAB9ATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146624-A | METHOD OF TREATING VIRUSES WITH BIS-BASIC KETONES OF DIBENZOFURAN | RICHARDSON-MERRELL INC. (US) | 1979-03-27 | — | — | US | claimed |
| US-4146624-A | METHOD OF TREATING VIRUSES WITH BIS-BASIC KETONES OF DIBENZOFURAN | RICHARDSON-MERRELL INC. (US) | 1979-03-27 | — | — | US | disclosed |