Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.71 |
| ▸ | TP53 | P04637 | 2/20 | 0.71 |
| ▸ | NPC1 | O15118 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 8/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MPI | P34949 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11794977 | 0.90 | L3MBTL1 (0.59) | ALDH1A1TP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11795205 | 0.88 | TSHR (0.60) | ALDH1A1TP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11729199 | 0.88 | L3MBTL1 (0.61) | ALDH1A1TP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11678069 | 0.87 | ALDH1A1 (0.67) | ALDH1A1TP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11801917 | 0.85 | ALDH1A1 (0.55) | ALDH1A1TP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11751985 | 0.85 | KDM4E (0.67) | ALDH1A1TP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11807793 | 0.84 | TSHR (0.55) | ALDH1A1TP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11797618 | 0.84 | KMT2A (0.62) | ALDH1A1TP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11859502 | 0.84 | ALDH1A1 (0.62) | ALDH1A1TP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11678838 | 0.83 | L3MBTL1 (0.68) | ALDH1A1TP53NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3957989-A | ADMINISTERING | RICHARDSON-MERRELL INC. (US) | 1976-05-18 | — | — | US | disclosed |