Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAPDH | P04406 | 1/20 | 0.41 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.41 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.41 |
| ▸ | CD44 | P16070 | 1/20 | 0.41 |
| ▸ | MSN | P26038 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11563527 | 0.82 | HSD17B10 (0.43) | KMT2ACYP1A2CYP3A4CYP2C9HPGD | |
| SCHEMBL6860121 | 0.81 | AKR1B1 (0.43) | KMT2ACYP1A2GAPDHHSPA1AHSPA8 | |
| SCHEMBL11985044 | 0.79 | AKR1B1 (0.45) | KMT2ASMN1; SMN2MAPTMEN1AKR1B1 | |
| SCHEMBL18359151 | 0.79 | AKR1B1 (0.45) | KMT2ASMN1; SMN2MAPTMEN1AKR1B1 | |
| SCHEMBL20786046 | 0.78 | PNMT (0.44) | KMT2ACYP1A2CYP3A4HSD17B10MAPT | |
| SCHEMBL16823947 | 0.78 | PNMT (0.44) | KMT2ACYP1A2CYP3A4HSD17B10MAPT | |
| SCHEMBL3948500 | 0.78 | PNMT (0.44) | KMT2ACYP1A2CYP3A4HSD17B10MAPT | |
| SCHEMBL22397109 | 0.77 | ADAMTS5 (0.52) | KMT2ACYP1A2CYP3A4CYP2C9HPGD | |
| SCHEMBL925042 | 0.77 | HPGD (0.48) | KMT2ACYP1A2CYP3A4CYP2C9HPGD | |
| SCHEMBL21819338 | 0.77 | ADAMTS5 (0.52) | KMT2ACYP1A2CYP3A4CYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4164576-A | LIPOGENESIS INHIBITORS IN MAMMALS | SHELL OIL COMPANY (US) | 1979-08-14 | — | — | US | disclosed |