Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SCN4A | P35499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3060996 | 0.79 | ENPP3 (0.41) | ALDH1A1POLBENPP3ENPP1ENPP2 | |
| SCHEMBL3803839 | 0.79 | ENPP3 (0.41) | ALDH1A1POLBENPP3ENPP1ENPP2 | |
| SCHEMBL16213017 | 0.74 | STAT3 (0.46) | ALDH1A1LMNASTAT3 | |
| SCHEMBL16213015 | 0.74 | STAT3 (0.46) | ALDH1A1LMNASTAT3 | |
| SCHEMBL16213013 | 0.74 | STAT3 (0.46) | ALDH1A1LMNASTAT3 | |
| SCHEMBL2706462 | 0.72 | PRCP (0.35) | LMNAMAPTKDM4E | |
| SCHEMBL10856644 | 0.72 | PRCP (0.35) | SCN4A | |
| SCHEMBL28911945 | 0.72 | PRCP (0.35) | LMNAMAPTKDM4E | |
| SCHEMBL675798 | 0.72 | PRCP (0.35) | LMNAMAPTKDM4E | |
| SCHEMBL2422874 | 0.72 | PRCP (0.35) | LMNAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154840-A | Antihypertensive pipecolic acid derivatives | E. R. SQUIBB & SONS, INC. (US) | 1979-05-15 | — | — | US | disclosed |
| US-4105776-A | ANGIOTENSIN CONVERTING ENZYME INHIBITORS, HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1978-08-08 | — | — | US | disclosed |