Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | NPC1 | O15118 | 3/20 | 0.70 |
| ▸ | RAB9A | P51151 | 3/20 | 0.70 |
| ▸ | TTR | P02766 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11356857 | 0.86 | TTR (0.56) | MEN1KMT2ANPC1RAB9ATTR | |
| SCHEMBL2907889 | 0.85 | TTR (0.54) | MEN1KMT2ANPC1RAB9ATTR | |
| SCHEMBL2907061 | 0.84 | TTR (0.53) | MEN1KMT2ANPC1RAB9ATTR | |
| SCHEMBL2907068 | 0.84 | TTR (0.53) | MEN1KMT2ANPC1RAB9ATTR | |
| SCHEMBL11389438 | 0.83 | MEN1 (0.53) | MEN1KMT2ANPC1RAB9ATTR | |
| SCHEMBL11544400 | 0.83 | MEN1 (0.68) | MEN1KMT2ANPC1RAB9ATTR | |
| SCHEMBL11362855 | 0.83 | RAB9A (0.51) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL11549538 | 0.83 | KDM4E (0.56) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL11389432 | 0.82 | MEN1 (0.51) | MEN1KMT2ANPC1RAB9ATTR | |
| SCHEMBL11551408 | 0.81 | MAOA (0.50) | MEN1KMT2ANPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4143042-A | ANTIALLERGENS, BRONCHODILATOR AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-03-06 | — | — | US | claimed |