Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MLYCD | O95822 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11548043 | 0.80 | NAAA (0.60) | NAAAL3MBTL1THRATHRBKDM4E | |
| SCHEMBL11147008 | 0.77 | CNR1 (0.60) | NAAAL3MBTL1CNR1KDM4EMLYCD | |
| SCHEMBL7968360 | 0.76 | NAAA (0.56) | NAAAL3MBTL1CNR1KDM4ESMN1; SMN2 | |
| SCHEMBL9979011 | 0.76 | NAAA (0.71) | NAAAL3MBTL1THRATHRBMLYCD | |
| SCHEMBL9979317 | 0.76 | NAAA (0.71) | NAAAL3MBTL1THRATHRBMLYCD | |
| SCHEMBL19326796 | 0.76 | NAAA (0.71) | NAAAL3MBTL1THRATHRBMLYCD | |
| SCHEMBL6437809 | 0.76 | NAAA (0.71) | NAAAL3MBTL1THRATHRBMLYCD | |
| SCHEMBL9978782 | 0.76 | NAAA (0.71) | NAAAL3MBTL1THRATHRBMLYCD | |
| SCHEMBL1978767 | 0.76 | NAAA (0.71) | NAAAL3MBTL1THRATHRBMLYCD | |
| SCHEMBL1977288 | 0.76 | NAAA (0.71) | NAAAL3MBTL1THRATHRBMLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4139623-A | HYPOTENSIVE AGENTS | C-G CORP. (US) | 1979-02-13 | — | — | US | disclosed |