Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6689602 | 1.00 | ALDH1A1 (0.44) | ALDH1A1HSD11B1EPAS1 | |
| SCHEMBL2011115 | 0.93 | ALDH1A1 (0.35) | ALDH1A1HSD11B1EPAS1 | |
| SCHEMBL212308 | 0.93 | ALDH1A1 (0.50) | ALDH1A1HSD11B1EPAS1 | |
| SCHEMBL2253089 | 0.93 | ALDH1A1 (0.50) | ALDH1A1HSD11B1EPAS1 | |
| SCHEMBL829179 | 0.93 | ALDH1A1 (0.40) | ALDH1A1HSD11B1EPAS1 | |
| SCHEMBL13464122 | 0.90 | ALDH1A1 (0.47) | ALDH1A1HSD11B1EPAS1 | |
| SCHEMBL6688863 | 0.90 | ALDH1A1 (0.47) | ALDH1A1HSD11B1EPAS1 | |
| SCHEMBL6277727 | 0.90 | ALDH1A1 (0.47) | ALDH1A1HSD11B1EPAS1 | |
| SCHEMBL30875827 | 0.90 | HSD11B1 (0.43) | ALDH1A1HSD11B1EPAS1 | |
| SCHEMBL20511602 | 0.86 | HSD11B1 (0.34) | ALDH1A1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110034628-A1 | BRANCHED POLYOLS CONTAINING ON AVERAGE TWO OR MORE HYDROXYL GROUPS PER MOLECULE,THEIR PREPARATION AND USE | BASF COATINGS AG (DE) | 2011-02-10 | — | — | US | claimed |
| EP-0082967-A2 | Traction fluid | Optimol-Ölwerke GmbH (DE) | 1983-07-06 | — | — | EP | claimed |
| EP-2493991-B1 | ANTIREFLECTIVE COMPOSITION FOR PHOTORESISTS | MERCK PATENT GMBH (DE) | 2016-03-02 | — | — | EP | disclosed |
| EP-1672050-B1 | LUBRICATING OIL COMPOSITION | IDEMITSU KOSAN CO (JP) | 2015-12-09 | — | — | EP | disclosed |
| EP-2009304-B1 | TORQUE LIMITER | JTEKT CORP (JP) | 2014-10-01 | — | — | EP | disclosed |
| EP-2003353-B1 | TORQUE LIMITER | JTEKT CORP (JP) | 2014-06-04 | — | — | EP | disclosed |
| US-8551686-B2 | Antireflective composition for photoresists | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2013-10-08 | — | — | US | disclosed |
| EP-2052293-B1 | ANTIREFLECTIVE COMPOSITION FOR PHOTORESISTS | AZ ELECTRONIC MATERIALS USA (US) | 2013-03-13 | — | — | EP | disclosed |
| EP-2493991-A1 | ANTIFEFLECTIVE COMPOSITION FOR PHOTORESISTS | AZ Electronic Materials USA Corp. (US) | 2012-09-05 | — | — | EP | disclosed |
| US-8230986-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-31 | — | — | US | disclosed |
| US-8220609-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-17 | — | — | US | disclosed |
| US-20080076059-A1 | Antireflective coating compositions | MERCK PATENT GMBH (DE) | 2008-03-27 | — | — | US | disclosed |
| WO-2008017954-A2 | ANTIREFLECTIVE COMPOSITION FOR PHOTORESISTS | AZ ELECTRONIC MATERIALS USA CORP. (DE) | 2008-02-14 | — | — | WO | disclosed |
| US-20080038659-A1 | Antireflective composition for photoresists | MERCK PATENT GMBH (DE) | 2008-02-14 | — | — | US | disclosed |
| US-20080021055-A1 | Novel cycloalkyl derivatives as inhibitors of bone resorption and vitronectin receptor antagonists | AVENTIS PHARMA S.A. | 2008-01-24 | — | — | US | disclosed |
| US-20070042915-A1 | Lube base oil and lubricating oil composition | IDEMITSU KOSAN CO., LTD. (JP) | 2007-02-22 | — | — | US | disclosed |
| EP-1672050-A1 | LUBE BASE OIL AND LUBRICATING OIL COMPOSITION | IDEMITSU KOSAN CO., LTD. (JP) | 2006-06-21 | — | — | EP | disclosed |
| US-6207663-B1 | AS INHIBITORS OF BONE RESORPTION, TUMOR GROWTH, TUMOR METASTASIS, OR INFLAMMATION, OR FOR THE TREATMENT OR PROPHYLAXIS OF CARDIOVASCULAR DISORDERS, NEPHROPATHIES OR RETINOPATHIES | HOECHST ATKIENGESELLSCHAFT (DE) | 2001-03-27 | — | — | US | disclosed |
| WO-1995014008-A1 | SUBSTITUTED 5-RING HETEROCYCLES, THEIR PREPARATION AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-05-26 | — | — | WO | disclosed |
| EP-0082967-A2 | Traction fluid | Optimol-Ölwerke GmbH (DE) | 1983-07-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021055-A1 | Novel cycloalkyl derivatives as inhibitors of bone resorption and vitronectin receptor antagonists | ADGRF1, ADGRE5, CALCR | ALDH1A1 3827/4885HSD11B1 2308/4885EPAS1 2529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.