Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.52 |
| ▸ | CES1 | P23141 | 2/20 | 0.52 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PAM | P19021 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11549787 | 1.00 | CES2 (0.52) | CES2CES1FNTAFNTBAKR1B1 | |
| SCHEMBL11478436 | 0.84 | GPR52 (0.50) | CES2CES1KMT2AMEN1GPR52 | |
| SCHEMBL11478439 | 0.84 | GPR52 (0.50) | CES2CES1KMT2AMEN1GPR52 | |
| SCHEMBL2373777 | 0.83 | CES2 (0.53) | CES2CES1RECQLKMT2ANPC1 | |
| SCHEMBL2373780 | 0.83 | CES2 (0.53) | CES2CES1RECQLKMT2ANPC1 | |
| SCHEMBL27580565 | 0.81 | RECQL (0.43) | CES2CES1RECQLKMT2AMEN1 | |
| SCHEMBL28349093 | 0.81 | AKT1 (0.43) | RECQLKMT2AMEN1RAB9A | |
| SCHEMBL2373805 | 0.80 | CES2 (0.56) | CES2CES1RECQLKMT2ATDP1 | |
| SCHEMBL2373801 | 0.80 | CES2 (0.56) | CES2CES1RECQLKMT2ATDP1 | |
| SCHEMBL11880987 | 0.79 | CES1 (0.59) | CES2CES1FNTAFNTBAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152136-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1979-05-01 | — | — | US | disclosed |