Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11550627 | 0.78 | KDM4E (0.61) | KMT2AMAPTALDH1A1POLBCYP1A2 | |
| SCHEMBL11550629 | 0.78 | KDM4E (0.61) | KMT2AMAPTALDH1A1POLBCYP1A2 | |
| SCHEMBL29248365 | 0.78 | KDM4E (0.65) | ABCG2KMT2ACYP1A2KDM4ETP53 | |
| SCHEMBL6431369 | 0.76 | TUBB4A (0.43) | ABCG2KMT2AMAPTALDH1A1POLB | |
| SCHEMBL6431367 | 0.76 | TUBB4A (0.43) | ABCG2KMT2AMAPTALDH1A1POLB | |
| SCHEMBL11549417 | 0.75 | NQO1 (0.54) | KMT2AMAPTALDH1A1CYP1A2KDM4E | |
| SCHEMBL11549421 | 0.75 | NQO1 (0.54) | KMT2AMAPTALDH1A1CYP1A2KDM4E | |
| SCHEMBL11549693 | 0.74 | CYP1A2 (0.62) | MAPTALDH1A1POLBCYP1A2KDM4E | |
| SCHEMBL11549689 | 0.74 | CYP1A2 (0.62) | MAPTALDH1A1POLBCYP1A2KDM4E | |
| SCHEMBL9097327 | 0.74 | POLB (0.49) | KMT2AALDH1A1POLBCYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172090-A | FROM ISOAZOLE AND BENZALDEHYDE | BASF AKTIENGESELLSCHAFT (DE) | 1979-10-23 | — | — | US | claimed |
| US-4172090-A | FROM ISOAZOLE AND BENZALDEHYDE | BASF AKTIENGESELLSCHAFT (DE) | 1979-10-23 | — | — | US | disclosed |