Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.47 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.46 |
| ▸ | TFEB | P19484 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11550627 | 1.00 | KDM4E (0.61) | KDM4EKMT2ALMNAPKMMAPT | |
| SCHEMBL1532464 | 0.80 | KDM4E (0.64) | KDM4EKMT2ALMNAPKMMAPT | |
| SCHEMBL11550297 | 0.78 | ABCG2 (0.46) | KDM4EKMT2ALMNAPKMMAPT | |
| SCHEMBL5555599 | 0.78 | ALDH1A1 (0.48) | KDM4EKMT2ALMNAPKMMAPT | |
| SCHEMBL5555600 | 0.78 | ALDH1A1 (0.48) | KDM4EKMT2ALMNAPKMMAPT | |
| SCHEMBL6337314 | 0.78 | NFE2L2 (0.53) | KDM4EKMT2ALMNAPKMMAPT | |
| SCHEMBL6337311 | 0.78 | NFE2L2 (0.53) | KDM4EKMT2ALMNAPKMMAPT | |
| SCHEMBL15740336 | 0.76 | KDM4E (1.00) | KDM4EKMT2ALMNAPKMMEN1 | |
| SCHEMBL15740335 | 0.76 | KDM4E (1.00) | KDM4EKMT2ALMNAPKMMEN1 | |
| SCHEMBL10533217 | 0.76 | KDM4E (0.54) | KDM4EKMT2ALMNAPKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172090-A | FROM ISOAZOLE AND BENZALDEHYDE | BASF AKTIENGESELLSCHAFT (DE) | 1979-10-23 | — | — | US | disclosed |