Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 4/20 | 0.37 |
| ▸ | PPARA | Q07869 | 5/20 | 0.35 |
| ▸ | PPARD | Q03181 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 3/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11548880 | 0.86 | NPC1 (0.39) | MAPTHAO1ALOX5ACACBMMP2 | |
| SCHEMBL11549319 | 0.86 | MAPT (0.41) | MAPTACACB | |
| SCHEMBL11551760 | 0.85 | MAPT (0.38) | MAPTHAO1PPARALTA4HNPC1 | |
| SCHEMBL11556810 | 0.85 | MAPT (0.38) | MAPTHAO1LTA4HNPC1RAB9A | |
| SCHEMBL11548494 | 0.85 | PARP10 (0.43) | MAPTL3MBTL1 | |
| SCHEMBL11552961 | 0.84 | HAO1 (0.49) | MAPTHAO1ALOX5MMP1MMP2 | |
| SCHEMBL11294629 | 0.81 | SMN1; SMN2 (0.41) | MAPTHAO1MMP2MMP9MMP13 | |
| SCHEMBL11550355 | 0.79 | MAPT (0.40) | MAPTHAO1LTA4HLMNAL3MBTL1 | |
| SCHEMBL11553523 | 0.79 | LPAR1 (0.40) | MAPTPPARAPPARDPPARGL3MBTL1 | |
| SCHEMBL11552212 | 0.78 | AR (0.40) | MAPTHAO1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151294-A | Alkynols and process for their preparation | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-04-24 | — | — | US | disclosed |