Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 9/20 | 0.40 |
| ▸ | LPAR5 | Q9H1C0 | 9/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11549075 | 0.86 | HTT (0.47) | PARP10LPAR1LPAR5MAPTHTT | |
| SCHEMBL11550385 | 0.85 | MAPT (0.38) | MAPTL3MBTL1 | |
| SCHEMBL11553523 | 0.84 | LPAR1 (0.40) | LPAR1LPAR5MAPTMMP14EGLN2 | |
| SCHEMBL11550355 | 0.84 | MAPT (0.40) | MAPTHTTNPSR1L3MBTL1 | |
| SCHEMBL11298354 | 0.78 | MMP2 (0.41) | MAPTHTTMMP14 | |
| SCHEMBL11548880 | 0.78 | NPC1 (0.39) | MAPTMMP14EGLN2EGLN1 | |
| SCHEMBL11549658 | 0.77 | MAPT (0.42) | MAPTHTTNPSR1L3MBTL1 | |
| SCHEMBL11548222 | 0.76 | PARP10 (0.43) | PARP10LPAR1LPAR5HTTEGLN2 | |
| SCHEMBL11556810 | 0.76 | MAPT (0.38) | MAPTL3MBTL1 | |
| SCHEMBL11551760 | 0.76 | MAPT (0.38) | MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151294-A | Alkynols and process for their preparation | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-04-24 | — | — | US | disclosed |