Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11556176 | 0.86 | HAO1 (0.44) | MAPTL3MBTL1SLC6A4HAO1SLC6A2 | |
| SCHEMBL11548494 | 0.84 | PARP10 (0.43) | MAPTL3MBTL1NPSR1HTT | |
| SCHEMBL11553523 | 0.84 | LPAR1 (0.40) | MAPTL3MBTL1NPSR1 | |
| SCHEMBL11556810 | 0.82 | MAPT (0.38) | MAPTL3MBTL1HAO1LMNAALDH1A1 | |
| SCHEMBL11550385 | 0.79 | MAPT (0.38) | MAPTL3MBTL1HAO1LMNALTA4H | |
| SCHEMBL11298354 | 0.78 | MMP2 (0.41) | MAPTLMNAALDH1A1HTT | |
| SCHEMBL11552067 | 0.78 | CYP2C9 (0.39) | MAPTNPSR1HAO1LMNAALDH1A1 | |
| SCHEMBL11555183 | 0.77 | MAPT (0.42) | MAPTRIPK1ALDH1A1MAPK1HTT | |
| SCHEMBL11551760 | 0.76 | MAPT (0.38) | MAPTL3MBTL1HAO1MEN1KMT2A | |
| SCHEMBL11048323 | 0.75 | MAPT (0.64) | MAPTNPSR1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151294-A | Alkynols and process for their preparation | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-04-24 | — | — | US | disclosed |