Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | F13A1 | P00488 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | QPCT | Q16769 | 1/20 | 0.43 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 5/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11546885 | 0.84 | KMT2A (0.41) | KDM4EF13A1SMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL4991609 | 0.83 | KMT2A (0.46) | KDM4ESMN1; SMN2ALDH1A1MAPTPOLB | |
| SCHEMBL11197065 | 0.81 | KMT2A (0.55) | KDM4ESMN1; SMN2ALDH1A1MAPTACACB | |
| SCHEMBL667359 | 0.78 | KDM4E (0.65) | KDM4EF13A1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL11547458 | 0.77 | ACHE (0.48) | — | |
| SCHEMBL2091579 | 0.75 | KDM4E (0.57) | KDM4EF13A1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL10592850 | 0.74 | KDM4E (0.84) | KDM4EF13A1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL5523315 | 0.74 | CYP11B1 (0.41) | KDM4EALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL15492721 | 0.72 | KDM4E (0.62) | KDM4EF13A1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL48869 | 0.72 | POLB (0.60) | KDM4EF13A1SMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4139623-A | HYPOTENSIVE AGENTS | C-G CORP. (US) | 1979-02-13 | — | — | US | disclosed |
| US-4027027-A | BETA-RECEPTOR-BLOCKERS, HYPOTENSIVES AND VALODILATORS; FOR TREATING ARRYTHMIAS AND ANGINA PECTORIS | CIBA-GEIGY CORPORATION (US) | 1977-05-31 | — | — | US | disclosed |