Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11197065 | 0.87 | KMT2A (0.55) | GLAKMT2AHRH4HRH3 | |
| SCHEMBL7666089 | 0.83 | ACHE (0.54) | ACHEGLAKMT2A | |
| SCHEMBL11546885 | 0.83 | KMT2A (0.41) | GLAKMT2A | |
| SCHEMBL5110887 | 0.77 | NPC1 (0.63) | ACHEGLAKMT2A | |
| SCHEMBL11550474 | 0.77 | KDM4E (0.51) | — | |
| SCHEMBL4769744 | 0.76 | KMT2A (0.57) | ACHEGLAKMT2A | |
| SCHEMBL21382248 | 0.76 | KMT2A (0.57) | ACHEGLAKMT2AHRH4HRH3 | |
| SCHEMBL8585756 | 0.75 | KMT2A (0.56) | ACHEGLAKMT2A | |
| SCHEMBL8803375 | 0.74 | CNR2 (0.53) | ACHEGLAKMT2A | |
| SCHEMBL27887140 | 0.74 | KMT2A (0.55) | ACHEGLAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4139623-A | HYPOTENSIVE AGENTS | C-G CORP. (US) | 1979-02-13 | — | — | US | disclosed |
| US-4027027-A | BETA-RECEPTOR-BLOCKERS, HYPOTENSIVES AND VALODILATORS; FOR TREATING ARRYTHMIAS AND ANGINA PECTORIS | CIBA-GEIGY CORPORATION (US) | 1977-05-31 | — | — | US | disclosed |