Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 2/20 | 0.50 |
| ▸ | PDE5A | O76074 | 17/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.49 |
| ▸ | PDE6C | P51160 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11551231 | 0.94 | MPL (0.50) | GUSBPDE5AHDAC6HDAC1HDAC2 | |
| SCHEMBL11553636 | 0.92 | GUSB (0.52) | GUSBPDE5AHDAC6HDAC1HDAC2 | |
| SCHEMBL11552844 | 0.85 | GUSB (0.49) | GUSBPDE5AHDAC6HDAC1HDAC2 | |
| SCHEMBL11554058 | 0.85 | GUSB (0.51) | GUSBPDE5AHDAC6HDAC1HDAC2 | |
| SCHEMBL11384695 | 0.84 | GUSB (0.71) | GUSBPDE5ANPC1TP53POLB | |
| SCHEMBL11556064 | 0.83 | GUSB (0.49) | GUSBPDE5AHDAC6HDAC1HDAC2 | |
| SCHEMBL11550603 | 0.81 | GUSB (0.47) | GUSBPDE5AHDAC6HDAC1HDAC2 | |
| SCHEMBL11556538 | 0.81 | TSHR (0.47) | GUSBNPC1TP53POLBMAPT | |
| SCHEMBL11375179 | 0.80 | PDE5A (0.45) | GUSBPDE5ANPC1TP53POLB | |
| SCHEMBL11553024 | 0.80 | GUSB (0.57) | GUSBPDE5ANPC1TP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159330-A | ANTIALLERGENS | CARLO ERBA S.P.A. (IT) | 1979-06-26 | — | — | US | disclosed |