Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | GUSB | P08236 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.43 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11554058 | 0.91 | GUSB (0.51) | KDM4EHSD17B10GUSBLMNAPDE5A | |
| SCHEMBL11555458 | 0.90 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDHSD17B10GUSB | |
| SCHEMBL11557400 | 0.87 | NPSR1 (0.47) | KDM4EALDH1A1HPGDHSD17B10GUSB | |
| SCHEMBL11551327 | 0.86 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDHSD17B10GUSB | |
| SCHEMBL11377673 | 0.85 | ALDH1A1 (0.57) | KDM4EALDH1A1HPGDHSD17B10GUSB | |
| SCHEMBL11549969 | 0.83 | GUSB (0.49) | KDM4EHSD17B10GUSBLMNAPDE5A | |
| SCHEMBL11556538 | 0.83 | TSHR (0.47) | KDM4EALDH1A1HPGDHSD17B10GUSB | |
| SCHEMBL11375840 | 0.82 | ALDH1A1 (0.58) | KDM4EALDH1A1HPGDHSD17B10GUSB | |
| SCHEMBL11553644 | 0.82 | ALDH1A1 (0.53) | KDM4EALDH1A1HPGDHSD17B10GUSB | |
| SCHEMBL11552844 | 0.82 | GUSB (0.49) | KDM4EALDH1A1HPGDHSD17B10GUSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159330-A | ANTIALLERGENS | CARLO ERBA S.P.A. (IT) | 1979-06-26 | — | — | US | disclosed |