Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | HPGD | P15428 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.45 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11375840 | 0.89 | ALDH1A1 (0.58) | ALDH1A1HPGDKDM4EHSD17B10PKN1 | |
| SCHEMBL11380547 | 0.88 | MGLL (0.48) | ALDH1A1HPGDKDM4EMGLLCYP1A2 | |
| SCHEMBL11550624 | 0.85 | KDM4E (0.54) | ALDH1A1HPGDKDM4EHSD17B10PKN1 | |
| SCHEMBL11551327 | 0.84 | ALDH1A1 (0.49) | ALDH1A1HPGDKDM4EHSD17B10PKN1 | |
| SCHEMBL11382440 | 0.83 | ALDH1A1 (0.50) | ALDH1A1HPGDKDM4EHSD17B10PKN1 | |
| SCHEMBL11381858 | 0.83 | ALDH1A1 (0.48) | ALDH1A1HPGDKDM4EHSD17B10PKN1 | |
| SCHEMBL11553644 | 0.82 | ALDH1A1 (0.53) | ALDH1A1HPGDKDM4EHSD17B10PKN1 | |
| SCHEMBL11381930 | 0.80 | ALDH1A1 (0.55) | ALDH1A1HPGDKDM4EHSD17B10PKN1 | |
| SCHEMBL11377089 | 0.80 | MEN1 (0.46) | ALDH1A1HPGDKDM4EHSD17B10MGLL | |
| SCHEMBL11556538 | 0.80 | TSHR (0.47) | ALDH1A1HPGDKDM4EHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | disclosed |