Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2 | P11137 | 12/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | PGR | P06401 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11554945 | 0.90 | MAP2 (0.60) | MAP2CA1CA2PGRKDM4E | |
| SCHEMBL11554157 | 0.88 | PGR (0.53) | MAP2CA1CA2PGRKDM4E | |
| SCHEMBL11551322 | 0.82 | ALDH1A1 (0.66) | MAP2PGRKDM4EALDH1A1HPGD | |
| SCHEMBL215430 | 0.79 | MAP2 (1.00) | MAP2CA1CA2KDM4EALDH1A1 | |
| SCHEMBL11403058 | 0.77 | MAP2 (1.00) | MAP2CA1CA2KDM4EALDH1A1 | |
| SCHEMBL11555822 | 0.77 | PGR (0.54) | PGRMEN1KMT2A | |
| SCHEMBL3878005 | 0.73 | KDR (0.60) | MAP2CA1CA2KDM4EALDH1A1 | |
| SCHEMBL18092674 | 0.72 | MAPT (0.81) | MAP2CA1CA2KDM4EALDH1A1 | |
| SCHEMBL14408800 | 0.72 | CA1 (0.62) | MAP2CA1CA2ALDH1A1MEN1 | |
| SCHEMBL1356850 | 0.71 | ALDH1A1 (0.70) | MAP2KDM4EALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156016-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1979-05-22 | — | — | US | disclosed |