Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | TP53 | P04637 | 5/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9277985 | 0.79 | TSHR (0.69) | TSHRHTTSMN1; SMN2HPGDNAAA | |
| SCHEMBL21827062 | 0.79 | TSHR (0.69) | TSHRHTTAPPSMN1; SMN2HPGD | |
| SCHEMBL12704467 | 0.78 | NAAA (0.74) | TSHRHTTMAPTTP53THRB | |
| SCHEMBL8527038 | 0.77 | DRD3 (0.55) | SIGMAR1DRD2DRD4DRD3 | |
| SCHEMBL11267483 | 0.76 | HPGD (0.68) | TSHRHTTMAPTTP53THRB | |
| Hydrochloric Acid SCHEMBL8528848 | 0.76 | DRD3 (0.54) | SIGMAR1DRD2DRD4DRD3 | |
| SCHEMBL7850828 | 0.74 | KMT2A (0.47) | MAPTMEN1KMT2ARXFP1GAA | |
| SCHEMBL11041038 | 0.73 | TSHR (0.64) | TSHRHTTSMN1; SMN2HPGDNAAA | |
| Acrylic Acid SCHEMBL21827420 | 0.72 | TSHR (0.57) | TSHRHTTMAPTTP53THRB | |
| SCHEMBL6762498 | 0.71 | NAAA (0.59) | TSHRHTTSMN1; SMN2GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172202-A | Process for the preparation of 4-amino-1,8-naphthalimides | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-10-23 | — | — | US | disclosed |