SCHEMBL11552154

SCHEMBL11552154

Cc1ccc(C=C(C#N)C=O)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 3/20 0.46
CYP2A6 P11509 1/20 0.45
KMT2A Q03164 5/20 0.43
ALDH1A1 P00352 5/20 0.43
MAPT P10636 4/20 0.43
MEN1 O00255 4/20 0.43
KDM4E B2RXH2 3/20 0.43
NPSR1 Q6W5P4 2/20 0.43
LMNA P02545 1/20 0.43
POLB P06746 1/20 0.43
HPGD P15428 3/20 0.43
PKM P14618 1/20 0.43
RAB9A P51151 1/20 0.42
ERBB2 P04626 1/20 0.41
TP53 P04637 1/20 0.39
USP2 O75604 1/20 0.39
RECQL P46063 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CISD1 Q9NZ45 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11552151 1.00 EGFR (0.46) EGFRCYP2A6KMT2AALDH1A1MAPT
SCHEMBL5805255 0.82 MEN1 (0.59) EGFRKMT2AALDH1A1MAPTMEN1
SCHEMBL28429180 0.82 MEN1 (0.59) EGFRKMT2AALDH1A1MAPTMEN1
SCHEMBL13620544 0.81 EGFR (0.46) EGFRKMT2AALDH1A1MAPTMEN1
SCHEMBL11553040 0.81 EGFR (0.46) EGFRKMT2AALDH1A1MAPTMEN1
SCHEMBL11553035 0.81 EGFR (0.46) EGFRKMT2AALDH1A1MAPTMEN1
SCHEMBL19499650 0.81 MAPT (0.43) EGFRKMT2AALDH1A1MAPTMEN1
SCHEMBL11551197 0.80 ALDH1A1 (0.64) CYP2A6KMT2AALDH1A1MAPTMEN1
SCHEMBL11551995 0.80 MAPT (0.67) CYP2A6KMT2AALDH1A1MAPTMEN1
SCHEMBL5805057 0.80 MAPT (0.67) CYP2A6KMT2AALDH1A1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7556918-B2 Color photographic films comprising support having color developable light sensitive silver halide emulsion layers and color dye-forming couplers, used for high speed print reproduction; storage stability FUJIFILM CORPORATION (JP) 2009-07-07 US disclosed
US-20080113305-A1 SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL FUJIFILM CORPORATION 2008-05-15 US disclosed
US-4172090-A FROM ISOAZOLE AND BENZALDEHYDE BASF AKTIENGESELLSCHAFT (DE) 1979-10-23 US disclosed