Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.37 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28429180 | 0.82 | MEN1 (0.59) | EGFRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL5805255 | 0.82 | MEN1 (0.59) | EGFRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL11553040 | 0.81 | EGFR (0.46) | EGFRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL11552154 | 0.81 | EGFR (0.46) | EGFRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL11552151 | 0.81 | EGFR (0.46) | EGFRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL11553035 | 0.81 | EGFR (0.46) | EGFRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL13265295 | 0.80 | MCL1 (0.52) | EGFRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL628778 | 0.80 | MCL1 (0.52) | EGFRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL4548765 | 0.80 | MCL1 (0.52) | EGFRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL11551197 | 0.77 | ALDH1A1 (0.64) | MAPTALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7621966-B2 | Cosmetic composition comprising at least one pigment and/or at least one filler surface-treated beforehand with at least one organic agent and at least one electrophilic monomer | L'OREAL S.A. (FR) | 2009-11-24 | — | — | US | disclosed |