Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | BHMT | Q93088 | 2/20 | 0.45 |
| ▸ | GNPAT | O15228 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.42 |
| ▸ | ICMT | O60725 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.41 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16097664 | 0.88 | MAPT (0.51) | MAPTALDH1A1BHMTGNPATKDM4E | |
| SCHEMBL11553457 | 0.88 | MAPT (0.51) | MAPTALDH1A1BHMTGNPATKDM4E | |
| SCHEMBL21144523 | 0.88 | MAPT (0.52) | MAPTALDH1A1GNPATKDM4ETHRB | |
| SCHEMBL29007209 | 0.85 | MAPT (0.46) | MAPTALDH1A1GNPATKDM4ETHRB | |
| SCHEMBL9544079 | 0.84 | GNPAT (0.47) | MAPTALDH1A1GNPATTHRBBLM | |
| SCHEMBL19927712 | 0.84 | ICMT (0.53) | MAPTALDH1A1KDM4ETHRBALOX15 | |
| SCHEMBL9545188 | 0.84 | ICMT (0.53) | MAPTALDH1A1KDM4ETHRBALOX15 | |
| SCHEMBL9545182 | 0.84 | ICMT (0.53) | MAPTALDH1A1KDM4ETHRBALOX15 | |
| SCHEMBL9119016 | 0.84 | ICMT (0.53) | MAPTALDH1A1KDM4ETHRBALOX15 | |
| SCHEMBL19927710 | 0.84 | ICMT (0.53) | MAPTALDH1A1KDM4ETHRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4002671-A | REDUCE SEBUM SECRETION ON SCALP OR SKIN | SOCIETE ANONYME DITE: L'OREAL (FR) | 1977-01-11 | — | — | US | claimed |
| US-4151301-A | ANTISECRETORY | L'OREAL (FR) | 1979-04-24 | — | — | US | disclosed |
| US-4002671-A | REDUCE SEBUM SECRETION ON SCALP OR SKIN | SOCIETE ANONYME DITE: L'OREAL (FR) | 1977-01-11 | — | — | US | disclosed |