Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | CES2 | O00748 | 3/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | GMNN | O75496 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9545188 | 1.00 | ICMT (0.53) | ICMTMAPTCES2THRBBLM | |
| SCHEMBL9119016 | 1.00 | ICMT (0.53) | ICMTMAPTCES2THRBBLM | |
| SCHEMBL19927710 | 1.00 | ICMT (0.53) | ICMTMAPTCES2THRBBLM | |
| SCHEMBL9117736 | 1.00 | ICMT (0.53) | ICMTMAPTCES2THRBBLM | |
| SCHEMBL19927712 | 1.00 | ICMT (0.53) | ICMTMAPTCES2THRBBLM | |
| SCHEMBL4953347 | 0.93 | ICMT (0.49) | ICMTMAPTCES2THRBBLM | |
| SCHEMBL23117309 | 0.92 | ICMT (0.50) | ICMTMAPTCES2THRBBLM | |
| SCHEMBL9275572 | 0.92 | ICMT (0.50) | ICMTMAPTCES2THRBBLM | |
| SCHEMBL23117307 | 0.92 | ICMT (0.50) | ICMTMAPTCES2THRBBLM | |
| SCHEMBL9275581 | 0.92 | ICMT (0.50) | ICMTMAPTCES2THRBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993021211-A1 | AMIDES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2, A PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LABORATORIOS MENARINI S.A. (ES) | 1993-10-28 | — | — | WO | disclosed |