Dazoxiben

Dazoxiben

SCHEMBL11554

O=C(O)c1ccc(OCCn2ccnc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 18/20 1.00
MEN1 O00255 1/20 0.97
LMNA P02545 1/20 0.97
KMT2A Q03164 1/20 0.97
KDM4E B2RXH2 1/20 0.65
ALDH1A1 P00352 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dazoxiben SCHEMBL4427771 0.99 TBXAS1 (0.97) TBXAS1MEN1LMNAKMT2AKDM4E
Dazoxiben SCHEMBL564080 0.99 TBXAS1 (1.00) TBXAS1MEN1LMNAKMT2A
SCHEMBL7502648 0.93 TBXAS1 (1.00) TBXAS1MEN1LMNAKMT2A
Dazoxiben SCHEMBL8372980 0.92 TBXAS1 (0.85) TBXAS1MEN1LMNAKMT2A
SCHEMBL22749387 0.91 TBXAS1 (0.90) TBXAS1MEN1LMNAKMT2AKDM4E
SCHEMBL8685423 0.88 TBXAS1 (0.80) TBXAS1MEN1LMNAKMT2A
SCHEMBL8690308 0.87 TBXAS1 (0.78) TBXAS1MEN1LMNAKMT2AKDM4E
SCHEMBL3005716 0.87 TBXAS1 (1.00) TBXAS1MEN1LMNAKMT2AKDM4E
SCHEMBL8690701 0.85 TBXAS1 (0.75) TBXAS1MEN1LMNAKMT2AKDM4E
Hydrochloric Acid SCHEMBL10751470 0.84 TBXAS1 (0.97) TBXAS1MEN1LMNAKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1439 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025184468-A9 MEASUREMENT OF URINE THROMBOXANE METABOLITES TO PREDICT SURVIVAL UNIVERSITY OF MASSACHUSETTS (US) 2025-10-16 WO claimed
US-20200187851-A1 PERIODONTAL DISEASE STRATIFICATION AND USES THEREOF THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 2020-06-18 US claimed
US-10570103-B2 Heterocyclic compounds useful in the treatment of disease EPIGEN BIOSCIENCES, INC. (US) 2020-02-25 US claimed
US-20190135767-A1 Heterocyclic Compounds Useful In The Treatment Of Disease EPIGEN BIOSCIENCES, INC. (US) 2019-05-09 US claimed
CN-106397171-A Synthesis method of dazoxiben medicine intermediate 4-(2-chloroethoxy) phenylformic acid 厦门安普顿信息科技有限公司 2017-02-15 CN claimed
CN-105481686-A Synthetic method of Dazoxiben drug intermediate 4-(2-chloroethoxy)benzoic acid CHENGDU QIESITE TECH CO LTD 2016-04-13 CN claimed
US-9221779-B2 Serotonin reuptake inhibitors as drugs having peripheral-system-restricted activity RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2015-12-29 US claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
EP-1675578-B9 INHIBITORS OF GLUTAMINYL AND GLUTAMATE CYCLASES FOR THE TREATMENT OF THE NEURODEGENERATIVE DISEASES FBD AND FDD PROBIODRUG AG (DE) 2014-06-25 EP claimed
CN-103664847-A Serotonin reuptake inhibitors as drugs having peripheral-system-restricted activity UNIV RAMOT 2014-03-26 CN claimed
EP-0266979-A2 Therapeutic agents IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-05-11 EP claimed
EP-0266980-A2 Pharmaceutical compositions, comprising a 2,4-diphenyl-1,3-dioxane derivative and an inhibitor of thromboxane A2 synthesis IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-05-11 EP claimed
EP-0256805-A2 Pharmaceutical compositions for the treatment of occlusive vascular diseases GLAXO GROUP LIMITED (GB) 1988-02-24 EP claimed
EP-0191771-A4 Automatic injector assembly. SURVIVAL TECHNOLOGY (US) 1987-12-07 EP claimed
WO-1986006965-A1 INJECTION METHOD AND APPARATUS WITH ELECTRICAL BLOOD ABSORBING STIMULATION SURVIVAL TECHNOLOGY, INC. (US) 1986-12-04 WO claimed
WO-1986005095-A1 t-PA COMPOSITION AND METHOD OF GETTING INTO BLOOD STREAM SURVIVAL TECHNOLOGY, INC. (US) 1986-09-12 WO claimed
EP-0191771-A1 Automatic injector assembly. SURVIVAL TECHNOLOGY (US) 1986-08-27 EP claimed
EP-0191056-A1 t-PA COMPOSITION AND METHOD OF GETTING INTO BLOOD STREAM SURVIVAL TECHNOLOGY, INC. (US) 1986-08-20 EP claimed
WO-1986001120-A1 INJECTION METHOD AND APPARATUS WITH ELECTRICAL BLOOD ABSORBING STIMULATION SURVIVAL TECHNOLOGY, INC. (US) 1986-02-27 WO claimed
WO-1986001104-A1 t-PA COMPOSITION AND METHOD OF GETTING INTO BLOOD STREAM SURVIVAL TECHNOLOGY, INC. (US) 1986-02-27 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190135767-A1 Heterocyclic Compounds Useful In The Treatment Of Disease LPAR1, LPAR2, LPAR4 TBXAS1 233/4885MEN1 2773/4885LMNA 1097/4885
US-10570103-B2 Heterocyclic compounds useful in the treatment of disease LPAR1, LPAR2, LPAR4 TBXAS1 233/4885MEN1 2773/4885LMNA 1097/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.