Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 16/20 | 0.75 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7394729 | 0.94 | TBXAS1 (0.78) | TBXAS1MEN1LMNAKMT2AMAPK1 | |
| SCHEMBL8685263 | 0.87 | TBXAS1 (0.88) | TBXAS1MEN1LMNAKMT2AKDM4E | |
| SCHEMBL8690308 | 0.86 | TBXAS1 (0.78) | TBXAS1MEN1LMNAKMT2AKDM4E | |
| SCHEMBL10751448 | 0.86 | TBXAS1 (1.00) | TBXAS1MEN1LMNAKMT2AKDM4E | |
| Dazoxiben SCHEMBL11554 | 0.85 | TBXAS1 (1.00) | TBXAS1MEN1LMNAKMT2AKDM4E | |
| SCHEMBL3005716 | 0.84 | TBXAS1 (1.00) | TBXAS1MEN1LMNAKMT2AKDM4E | |
| Dazoxiben SCHEMBL564080 | 0.84 | TBXAS1 (1.00) | TBXAS1MEN1LMNAKMT2A | |
| Dazoxiben SCHEMBL4427771 | 0.84 | TBXAS1 (0.97) | TBXAS1MEN1LMNAKMT2AKDM4E | |
| SCHEMBL10861586 | 0.84 | TBXAS1 (0.69) | TBXAS1MEN1LMNAKMT2AKDM4E | |
| SCHEMBL10750647 | 0.84 | TBXAS1 (1.00) | TBXAS1MEN1LMNAKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708171-A | HISTAMINE H3-RECEPTOR ANTAGONIST | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1998-01-13 | — | — | US | disclosed |