Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.66 |
| ▸ | TFEB | P19484 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | BCHE | P06276 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11554121 | 1.00 | NFE2L2 (0.66) | NFE2L2TFEBKDM4EMAPTNPC1 | |
| SCHEMBL31202230 | 0.80 | NFE2L2 (0.74) | NFE2L2TFEBKDM4EMAPTNPC1 | |
| SCHEMBL1569432 | 0.80 | NFE2L2 (0.74) | NFE2L2TFEBKDM4EMAPTNPC1 | |
| SCHEMBL7068436 | 0.80 | NFE2L2 (0.74) | NFE2L2TFEBKDM4EMAPTNPC1 | |
| SCHEMBL1569425 | 0.80 | NFE2L2 (0.74) | NFE2L2TFEBKDM4EMAPTNPC1 | |
| SCHEMBL2744044 | 0.80 | NFE2L2 (1.00) | NFE2L2TFEBKDM4EMAPTNPC1 | |
| SCHEMBL2744047 | 0.80 | NFE2L2 (1.00) | NFE2L2TFEBKDM4EMAPTNPC1 | |
| SCHEMBL29805195 | 0.80 | NFE2L2 (1.00) | NFE2L2TFEBKDM4EMAPTNPC1 | |
| SCHEMBL16403662 | 0.80 | NFE2L2 (1.00) | NFE2L2TFEBKDM4EMAPTNPC1 | |
| SCHEMBL30307386 | 0.80 | NFE2L2 (1.00) | NFE2L2TFEBKDM4EMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4171378-A | INSECTICIDES, VIRICIDES | STERLING DRUG INC. (US) | 1979-10-16 | — | — | US | disclosed |