Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.62 |
| ▸ | CCKBR | P32239 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11552056 | 0.84 | OPRK1 (0.70) | OPRK1PDE4DCCKBRALDH1A1HPGD | |
| SCHEMBL11776339 | 0.82 | OPRK1 (0.67) | OPRK1PDE4DCCKBRALDH1A1HPGD | |
| SCHEMBL11754667 | 0.82 | OPRK1 (0.70) | OPRK1PDE4DCCKBRALDH1A1HPGD | |
| SCHEMBL11550187 | 0.82 | OPRK1 (0.66) | OPRK1PDE4DALDH1A1HPGDCYP1A2 | |
| SCHEMBL11776991 | 0.81 | OPRK1 (0.65) | OPRK1PDE4DCCKBRALDH1A1HPGD | |
| SCHEMBL11552115 | 0.81 | OPRK1 (0.62) | OPRK1PDE4DCCKBRALDH1A1HPGD | |
| SCHEMBL11761654 | 0.80 | OPRK1 (0.67) | OPRK1PDE4DCCKBRHPGDKMO | |
| SCHEMBL11778247 | 0.80 | OPRK1 (0.64) | OPRK1PDE4DCCKBRALDH1A1HPGD | |
| SCHEMBL11776232 | 0.79 | OPRK1 (0.66) | OPRK1PDE4DCCKBRALDH1A1HPGD | |
| SCHEMBL11780361 | 0.79 | OPRK1 (0.66) | OPRK1PDE4DCCKBRALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3984398-A | 1,5-Benzodiazepine-2,4-diones | ROUSSEL-UCLAF (FR) | 1976-10-05 | — | — | US | claimed |
| US-4138572-A | Malonanilic derivatives | ROUSSEL UCLAF (FR) | 1979-02-06 | — | — | US | disclosed |
| US-4001408-A | SUBSTITUTED HETEROCYCLIC COMPOUNDS, PROCESSES AND COMPOSITION INCLUDING THOSE | ROUSSEL-UCLAF (FR) | 1977-01-04 | — | — | US | disclosed |
| US-3984398-A | 1,5-Benzodiazepine-2,4-diones | ROUSSEL-UCLAF (FR) | 1976-10-05 | — | — | US | disclosed |