SCHEMBL1155415

SCHEMBL1155415

Cc1ccc([I+]c2ccccc2)cc1.Fc1c(F)c(F)c([B-](c2c(F)c(F)c(F)c(F)c2F)(c2c(F)c(F)c(F)c(F)c2F)c2c(F)c(F)c(F)c(F)c2F)c(F)c1F

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.34
LMNA P02545 1/20 0.34
TSHR P16473 1/20 0.34
ALOX12 P18054 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
HPGD P15428 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
HTT P42858 1/20 0.31
NPC1 O15118 1/20 0.31
POLB P06746 1/20 0.31
NFKB1 P19838 1/20 0.31
RAB9A P51151 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toliodium SCHEMBL1155683 0.93 ACHE (0.37) ACHETDP1
Toliodium SCHEMBL29810005 0.90 ACHE (0.32) ACHELMNATSHRALOX12
SCHEMBL132586 0.89
Hydrogen Sulfide SCHEMBL30375675 0.87
SCHEMBL21679593 0.83
Toluene SCHEMBL27946707 0.82 ACHE (0.52) ACHELMNATSHRALOX12SMN1; SMN2
SCHEMBL133838 0.81 SCN5A (0.31) ACHE
SCHEMBL3753882 0.81 TSHR (0.48) ACHELMNATSHRNPC1RAB9A
SCHEMBL2579597 0.81 CA4 (0.41) LMNATDP1NPC1RAB9ARELA
SCHEMBL1001143 0.81 CA4 (0.41) LMNATDP1NPC1RAB9ARELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100039684-A1 SENSITIZER DYES FOR PHOTOACID GENERATING SYSTEMS USING SHORT VISIBLE WAVELENGTHS FORCETEC CO., LTD. (KR) 2010-02-18 US claimed
EP-2054770-A2 SENSITIZER DYES FOR PHOTOACID GENERATING SYSTEMS USING SHORT VISIBLE WAVELENGTHS STX Aprilis, Inc. (US) 2009-05-06 EP claimed
WO-2008021208-A2 SENSITIZER DYES FOR PHOTOACID GENERATING SYSTEMS USING SHORT VISIBLE WAVELENGTHS STX APRILIS, INC. (US) 2008-02-21 WO claimed
EP-1578870-A2 SENSITIZER DYES FOR PHOTOACID GENERATING SYSTEMS Aprilis, Inc. (US) 2005-09-28 EP claimed
WO-2004059389-A2 SENSITIZER DYES FOR PHOTOACID GENERATING SYSTEMS APRILIS, INC. (US) 2004-07-15 WO claimed
EP-3288997-B1 ADHESIVE COMPOSITIONS POWDERTECH BICESTER LTD (GB) 2020-12-30 EP disclosed
US-10689547-B2 Adhesive compositions POWDERTECH (BICESTER) LIMITED (GB) 2020-06-23 US disclosed
US-20180355214-A1 ADHESIVE COMPOSITIONS POWDERTECH (BICESTER) LIMITED (GB) 2018-12-13 US disclosed
EP-3288997-A1 ADHESIVE COMPOSITIONS Powdertech (Bicester) Limited (GB) 2018-03-07 EP disclosed
WO-2016174469-A1 ADHESIVE COMPOSITIONS POWDERTECH (BICESTER) LIMITED (GB) 2016-11-03 WO disclosed
US-20130075670-A1 AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS PLEXTRONICS, INC. (US) 2013-03-28 US disclosed
US-8283002-B2 Aminobenzene compositions and related devices and methods PLEXTRONICS, INC. (US) 2012-10-09 US disclosed
US-20060019197-A1 Sensitizer dyes for photoacid generating systems APRILIS, INC. (US) 2006-01-26 US disclosed
EP-1591097-A1 Cationically curing two component materials containing a noble metal catalyst 3M Espe AG (DE) 2005-11-02 EP disclosed
EP-1578870-A2 SENSITIZER DYES FOR PHOTOACID GENERATING SYSTEMS Aprilis, Inc. (US) 2005-09-28 EP disclosed
US-20040249181-A1 Holographic storage medium comprising polyfunctional epoxy monomers capable of undergoing cationic polymerization APRILIS, INC. 2004-12-09 US disclosed
US-6784300-B2 MONOMER/OLIGOMER LINKED BY SILOXANE TO A SILICON ATOM, BINDERS, AN ACID GERNERATOR WHEN EXPOSED TO ACTINIC RADIATION AND A SENSITIZER APRILIS, INC. 2004-08-31 US disclosed
WO-2004059389-A2 SENSITIZER DYES FOR PHOTOACID GENERATING SYSTEMS APRILIS, INC. (US) 2004-07-15 WO disclosed
US-6613437-B1 Two-component preparations comprising components (I) and (II), wherein at least one component comprises epoxy compounds and the preparations cure by cationic polymerization, initiated by Lewis and/or Bronsted acids, after mixing of the two 3M ESPE AG (DE) 2003-09-02 US disclosed
US-20020068223-A1 Holographic storage medium comprising polyfunctional epoxy monomers capable of undergoing cationic polymerization APRILIS, INC. 2002-06-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130075670-A1 AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS HLA-B, AAAS, SLCO2B1 ACHE 1023/4885LMNA 3728/4885TSHR 4376/4885
US-20020068223-A1 Holographic storage medium comprising polyfunctional epoxy monomers capable of undergoing cationic polymerization NEFM, EMD, PCNA ACHE 3802/4885LMNA 571/4885TSHR 4772/4885
US-20040249181-A1 Holographic storage medium comprising polyfunctional epoxy monomers capable of undergoing cationic polymerization NEFM, EMD, PCNA ACHE 3802/4885LMNA 571/4885TSHR 4772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.