Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.47 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365880 | 0.85 | MAPT (0.60) | MAPTKMT2AALDH1A1HPGDGPR35 | |
| SCHEMBL7996823 | 0.84 | MAPT (0.64) | MAPTKMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL1131511 | 0.81 | ALDH1A1 (0.62) | MAPTKMT2AALDH1A1HPGDCYP1A2 | |
| SCHEMBL978709 | 0.81 | TSHR (0.62) | MAPTKMT2AALDH1A1HPGDCYP1A2 | |
| SCHEMBL2614942 | 0.81 | TDP1 (0.58) | MAPTKMT2AALDH1A1RECQLHSD17B10 | |
| SCHEMBL30692252 | 0.81 | TDP1 (0.58) | MAPTKMT2AALDH1A1RECQLHSD17B10 | |
| SCHEMBL8616062 | 0.81 | MAPT (0.55) | MAPTKMT2AALDH1A1HPGDCYP1A2 | |
| SCHEMBL9387603 | 0.81 | TDP1 (0.55) | MAPTKMT2AALDH1A1HPGDGPR35 | |
| SCHEMBL29702896 | 0.81 | TDP1 (0.55) | MAPTKMT2AALDH1A1HPGDGPR35 | |
| SCHEMBL15177817 | 0.79 | MAPT (0.54) | MAPTKMT2AALDH1A1HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4137228-A | HIGH TINCTORIAL STRENGTH, COLORFASTNESS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1979-01-30 | — | — | US | disclosed |
| US-4033945-A | Water-soluble trisazo 8-amino-naphthol-1 dyes | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1977-07-05 | — | — | US | disclosed |