Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 1/20 | 0.49 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CRHBP | P24387 | 2/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9216468 | 0.84 | MAPT (0.60) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL30957522 | 0.84 | MAPT (0.60) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL11554160 | 0.84 | MAPT (0.56) | MAPTALDH1A1HSD17B10RECQLMEN1 | |
| SCHEMBL1131511 | 0.84 | ALDH1A1 (0.62) | MAPTALDH1A1HSD17B10RECQLMEN1 | |
| SCHEMBL365880 | 0.84 | MAPT (0.60) | MAPTALDH1A1HSD17B10RECQLMEN1 | |
| SCHEMBL30692252 | 0.84 | TDP1 (0.58) | MAPTALDH1A1HSD17B10RECQLMEN1 | |
| SCHEMBL2614942 | 0.84 | TDP1 (0.58) | MAPTALDH1A1HSD17B10RECQLMEN1 | |
| SCHEMBL5177187 | 0.84 | ALDH1A1 (0.64) | MAPTALDH1A1HSD17B10RECQLMEN1 | |
| SCHEMBL7703266 | 0.82 | ALDH1A1 (0.56) | MAPTALDH1A1HSD17B10RECQLMEN1 | |
| SCHEMBL11875548 | 0.82 | MAPT (0.58) | MAPTALDH1A1HSD17B10RECQLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015183518-A1 | SYNTHESIS OF AND CURING ADDITIVES FOR PHTHALONITRILES | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2015-12-03 | — | — | WO | disclosed |
| US-20150086551-A1 | Novel Therapeutic Agents | CRYSTAL BIOPHARMACEUTICAL LLC | 2015-03-26 | — | — | US | disclosed |
| US-6280884-B1 | HOLOGRAPHIC STORAGE IN PHOTOREFRACTIVE POLYMERIC OPTICAL ARTICLE, EXPOSURE TO ELECTROMAGNETIC RADIATION WITH INTERSECTING BEAMS | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2001-08-28 | — | — | US | disclosed |
| US-5607799-A | NONPHOTOCONDUCTIVE POLYMER, BENZIMIDAZOLINE, SENSITIZER | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1997-03-04 | — | — | US | disclosed |
| US-5361148-A | Apparatus for photorefractive two beam coupling | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1994-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150086551-A1 | Novel Therapeutic Agents | HDAC1, HDAC11, HDAC5 | MAPT 4240/4885ALDH1A1 779/4885HSD17B10 1196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.