Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | HTR6 | P50406 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11558054 | 0.90 | ACLY (0.49) | MAPTSIGMAR1KMT2ATP53CYP1A2 | |
| SCHEMBL11555416 | 0.85 | ALDH1A1 (0.57) | MAPTKMT2ACYP1A2HTR1ACYP2D6 | |
| Hydrochloric Acid SCHEMBL11560746 | 0.84 | ALDH1A1 (0.56) | MAPTKMT2ACYP1A2HTR1ACYP2D6 | |
| SCHEMBL11561314 | 0.78 | CSF1R (0.46) | MAPTKMT2ACYP3A4DRD3TSHR | |
| SCHEMBL11557398 | 0.77 | GRIK1 (0.43) | MAPTKMT2AHTR6HTR3AALDH1A1 | |
| SCHEMBL11555589 | 0.77 | GRIK1 (0.43) | MAPTKMT2AMEN1HTR3AALDH1A1 | |
| SCHEMBL11557912 | 0.77 | WEE1 (0.49) | KMT2ACYP1A2HTR6MEN1SMN1; SMN2 | |
| SCHEMBL6753291 | 0.77 | ALDH1A1 (0.57) | CYP1A2TSHRALDH1A1POLBMPO | |
| SCHEMBL11560087 | 0.77 | GRIK1 (0.43) | MAPTSIGMAR1HTR3AALDH1A1TRPV4 | |
| SCHEMBL9168453 | 0.76 | HTR1D (0.50) | CYP1A2HTR1ACYP2D6DRD2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4139634-A | ANTIDEPRESSANTS, ANTIAGGRESSION AGENTS, ANESTHETICS | LABAZ (FR) | 1979-02-13 | — | — | US | disclosed |