Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.45 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.44 |
| ▸ | CHRNG | P07510 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30149977 | 0.85 | PKM (0.58) | PARP1ALDH1A1HPGDHTTGAA | |
| SCHEMBL30149976 | 0.85 | PKM (0.58) | PARP1ALDH1A1HPGDHTTGAA | |
| SCHEMBL254975 | 0.85 | PKM (0.58) | PARP1ALDH1A1HPGDHTTGAA | |
| SCHEMBL9825357 | 0.81 | PARP1 (0.53) | PARP1ALDH1A1HPGDHTTGAA | |
| SCHEMBL11770290 | 0.80 | ALDH1A1 (0.55) | PARP1ALDH1A1HPGDHTTGAA | |
| SCHEMBL6832775 | 0.79 | HPGD (0.61) | PARP1HPGDPOLBMEN1KMT2A | |
| SCHEMBL2467642 | 0.79 | PARP1 (0.57) | PARP1ALDH1A1GAAMAPTMEN1 | |
| SCHEMBL111914 | 0.79 | HPGD (0.51) | PARP1ALDH1A1HPGDHTTGAA | |
| Hydrochloric Acid SCHEMBL11761257 | 0.79 | ALDH1A1 (0.54) | PARP1ALDH1A1HPGDHTTGAA | |
| SCHEMBL30424341 | 0.78 | PARP1 (0.58) | PARP1ALDH1A1HPGDHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151169-A | DECYCLIZATION, CYCLIZATION | GRUPPO LEPETIT (IT) | 1979-04-24 | — | — | US | disclosed |
| US-4119635-A | SEDATIVES, HYPNOTICS, TRANQUILIZERS | GRUPPO LEPETIT S.P.A. (IT) | 1978-10-10 | — | — | US | disclosed |