Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | ABL1 | P00519 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | GALK1 | P51570 | 3/20 | 0.36 |
| ▸ | BLM | P54132 | 3/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | TDP2 | O95551 | 3/20 | 0.36 |
| ▸ | KDM4A | O75164 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MPI | P34949 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12149795 | 0.74 | KDM4C (0.41) | LMNAKDM4CNPC1ABL1POLB | |
| SCHEMBL13760637 | 0.69 | TNF (0.32) | — | |
| SCHEMBL3540959 | 0.69 | ADORA2B (0.36) | MAPTKMT2ARECQLTSHRADORA2A | |
| SCHEMBL12149800 | 0.69 | KDM4E (0.32) | LMNAKDM4CNPC1ABL1POLB | |
| SCHEMBL12561756 | 0.67 | — | — | |
| SCHEMBL20803476 | 0.67 | — | — | |
| SCHEMBL2704481 | 0.66 | KMT2A (0.59) | MAPTL3MBTL1KMT2ARXFP1ALDH1A1 | |
| SCHEMBL141994 | 0.65 | GSK3A (0.44) | POLBHTTPIK3CDPIK3CAPIK3CB | |
| SCHEMBL13024710 | 0.64 | ATAD2 (0.39) | LMNAPOLBKDM4EHTTALDH1A1 | |
| SCHEMBL13470502 | 0.62 | CA12 (0.31) | CA12CA1CA2CA3CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4174445-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-11-13 | — | — | US | disclosed |
| US-4048315-A | NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-13 | — | — | US | disclosed |