Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11549471 | 0.92 | GUSB (0.53) | GUSBNPC1TP53POLBMAPT | |
| SCHEMBL11551096 | 0.91 | GUSB (0.48) | GUSBNPC1TP53POLBMAPT | |
| SCHEMBL11374673 | 0.88 | GUSB (0.58) | GUSBNPC1TP53POLBMAPT | |
| SCHEMBL11549248 | 0.86 | GUSB (0.56) | GUSBNPC1TP53POLBMAPT | |
| SCHEMBL11554055 | 0.86 | GUSB (0.55) | GUSBNPC1TP53POLBMAPT | |
| SCHEMBL11553024 | 0.86 | GUSB (0.57) | GUSBNPC1TP53POLBMAPT | |
| SCHEMBL11550702 | 0.84 | GUSB (0.42) | GUSBNPC1TP53POLBMAPT | |
| SCHEMBL11556023 | 0.84 | GUSB (0.51) | GUSBNPC1TP53POLBMAPT | |
| SCHEMBL11553336 | 0.84 | GUSB (0.51) | GUSBNPC1TP53POLBMAPT | |
| SCHEMBL11553644 | 0.83 | ALDH1A1 (0.53) | GUSBNPC1TP53POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159330-A | ANTIALLERGENS | CARLO ERBA S.P.A. (IT) | 1979-06-26 | — | — | US | disclosed |