Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | PDE5A | O76074 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11549471 | 0.91 | GUSB (0.53) | GUSBPDE5ATP53NPC1POLB | |
| SCHEMBL11554449 | 0.91 | GUSB (0.47) | GUSBPDE5ATP53NPC1POLB | |
| SCHEMBL11549248 | 0.88 | GUSB (0.56) | GUSBTP53NPC1POLBMAPT | |
| SCHEMBL11380722 | 0.87 | PDE5A (0.59) | GUSBPDE5ATP53NPC1POLB | |
| SCHEMBL11554055 | 0.85 | GUSB (0.55) | GUSBPDE5ATP53NPC1POLB | |
| SCHEMBL11553024 | 0.85 | GUSB (0.57) | GUSBPDE5ATP53NPC1POLB | |
| SCHEMBL11375259 | 0.84 | PDE5A (0.58) | GUSBPDE5AMAPTMEN1KMT2A | |
| SCHEMBL11553336 | 0.84 | GUSB (0.51) | GUSBPDE5ATP53NPC1POLB | |
| SCHEMBL11556023 | 0.84 | GUSB (0.51) | GUSBPDE5ATP53NPC1POLB | |
| SCHEMBL11554463 | 0.83 | GUSB (0.51) | GUSBPDE5ATP53NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159330-A | ANTIALLERGENS | CARLO ERBA S.P.A. (IT) | 1979-06-26 | — | — | US | claimed |
| US-4159330-A | ANTIALLERGENS | CARLO ERBA S.P.A. (IT) | 1979-06-26 | — | — | US | disclosed |