Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PDE5A | O76074 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11553799 | 0.93 | GUSB (0.44) | GUSBALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11553644 | 0.90 | ALDH1A1 (0.53) | GUSBALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11556023 | 0.88 | GUSB (0.51) | GUSBALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11549471 | 0.86 | GUSB (0.53) | GUSBMAPTPDE5AKMT2APOLB | |
| SCHEMBL11549502 | 0.85 | MEN1 (0.46) | GUSBALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11553336 | 0.84 | GUSB (0.51) | GUSBMAPTPDE5AKMT2APOLB | |
| SCHEMBL11555458 | 0.84 | ALDH1A1 (0.46) | GUSBALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11553024 | 0.80 | GUSB (0.57) | GUSBALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11375840 | 0.80 | ALDH1A1 (0.58) | GUSBALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11554449 | 0.80 | GUSB (0.47) | GUSBMAPTPDE5AKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159330-A | ANTIALLERGENS | CARLO ERBA S.P.A. (IT) | 1979-06-26 | — | — | US | claimed |
| US-4159330-A | ANTIALLERGENS | CARLO ERBA S.P.A. (IT) | 1979-06-26 | — | — | US | disclosed |