Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11546036 | 0.85 | PPARG (0.38) | PPARGPPARDPPARA | |
| SCHEMBL1039278 | 0.72 | PPARG (0.49) | PPARGPPARDPPARA | |
| SCHEMBL12929962 | 0.70 | — | — | |
| SCHEMBL1646908 | 0.67 | PPARG (0.40) | PPARGPPARDPPARA | |
| SCHEMBL9749472 | 0.67 | MAPT (0.35) | — | |
| SCHEMBL17468172 | 0.65 | — | — | |
| SCHEMBL17918189 | 0.64 | KMT2A (0.33) | — | |
| SCHEMBL6595412 | 0.63 | HSD11B1 (0.30) | — | |
| SCHEMBL6595416 | 0.61 | — | — | |
| SCHEMBL657653 | 0.61 | HSD11B1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4133816-A | Preparation of cis-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo[b,d]pyran-9-ones and intermediates therefor | ELI LILLY AND COMPANY (US) | 1979-01-09 | — | — | US | disclosed |
| US-4115403-A | Preparation of cis-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo [b,d]pyran-9-ones and intermediates therefor | ELI LILLY AND COMPANY (US) | 1978-09-19 | — | — | US | disclosed |
| US-4054581-A | Preparation of cis-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo[b,d]pyran-9-ones and intermediates therefor | ELI LILLY AND COMPANY (US) | 1977-10-18 | — | — | US | disclosed |