Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 3/20 | 0.31 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.31 |
| ▸ | GALR3 | O60755 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2711074 | 0.83 | KDM4E (0.35) | LMNAALDH1A1 | |
| SCHEMBL430973 | 0.78 | MAPT (0.42) | MAPTHPGDNPC1SMN1; SMN2RAB9A | |
| SCHEMBL876978 | 0.72 | LGMN (0.38) | MAPTNPC1RAB9ALMNAAPOBEC3A | |
| SCHEMBL13004982 | 0.72 | MAPT (0.34) | MAPTHPGDNPC1SMN1; SMN2RAB9A | |
| SCHEMBL1160912 | 0.67 | APOBEC3A (0.41) | MAPTNPC1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL11555151 | 0.67 | PPARG (0.38) | — | |
| SCHEMBL11449820 | 0.66 | GRIN1 (0.37) | — | |
| SCHEMBL28769174 | 0.65 | MAPT (0.36) | MAPTHPGDNPC1SMN1; SMN2RAB9A | |
| SCHEMBL6595412 | 0.62 | HSD11B1 (0.30) | — | |
| SCHEMBL612703 | 0.61 | LGMN (0.37) | MAPTHPGDNPC1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116840-A | Antiulcer, antiinflammatory, hypotensive, immunosuppressants | SCHERING CORPORATION (US) | 1992-05-26 | — | — | US | disclosed |
| US-4810708-A | ANTIALLERGY, IMMUNOSUPPRESSIVE | SCHERING CORPORATION (US) | 1989-03-07 | — | — | US | disclosed |