Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11563927 | 0.83 | ESR1 (0.38) | NPSR1ALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL11559884 | 0.82 | TSHR (0.39) | NPSR1ALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL11560055 | 0.81 | HRH4 (0.34) | — | |
| SCHEMBL11561872 | 0.79 | GAA (0.38) | NPSR1ALDH1A1MAPTHPGDGAA | |
| SCHEMBL11560739 | 0.68 | NQO2 (0.40) | CYP1A2CYP2C19NPSR1ALDH1A1HSD17B10 | |
| SCHEMBL10845230 | 0.63 | NPC1 (0.61) | CYP1A2CYP2C19NPSR1ALDH1A1MAPT | |
| SCHEMBL2390162 | 0.62 | CYP1A2 (0.66) | CYP1A2CYP2C19NPSR1ALDH1A1HSD17B10 | |
| SCHEMBL11903830 | 0.61 | MAPT (0.61) | CYP1A2CYP2C19NPSR1ALDH1A1HSD17B10 | |
| SCHEMBL15799957 | 0.61 | FTO (0.52) | CYP1A2CYP2C19NPSR1ALDH1A1MAPT | |
| SCHEMBL11248254 | 0.60 | CYP1A2 (0.54) | CYP1A2CYP2C19NPSR1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134974-A | Imidazo[5,1-c][1,4]benzoxazin-1-one | CARLO ERBA S. P. A. (IT) | 1979-01-16 | — | — | US | disclosed |