Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11558080 | 0.82 | MAPT (0.36) | CYP1A2CYP2C19ALDH1A1MAPTBRD4 | |
| SCHEMBL11558220 | 0.80 | KCNE1 (0.34) | TRPV1 | |
| SCHEMBL11560192 | 0.80 | LMNA (0.38) | NPSR1SMN1; SMN2TRPV1 | |
| SCHEMBL11565708 | 0.78 | PTGS2 (0.34) | BRD4CREBBP | |
| SCHEMBL11559426 | 0.78 | TRPV1 (0.35) | CYP2C19MEN1KMT2ATRPV1 | |
| SCHEMBL11555223 | 0.68 | CYP1A2 (0.40) | CYP1A2CYP2C19NPSR1ALDH1A1HSD17B10 | |
| SCHEMBL11560680 | 0.63 | LMNA (0.38) | CYP1A2CYP2C19NPSR1ALDH1A1HSD17B10 | |
| SCHEMBL6892008 | 0.62 | CYP1A2 (0.44) | CYP1A2CYP2C19NPSR1ALDH1A1HSD17B10 | |
| SCHEMBL11608411 | 0.62 | CYP1A2 (0.44) | CYP1A2CYP2C19NPSR1MAPTTHRB | |
| SCHEMBL11608423 | 0.62 | CYP1A2 (0.44) | CYP1A2CYP2C19NPSR1MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134974-A | Imidazo[5,1-c][1,4]benzoxazin-1-one | CARLO ERBA S. P. A. (IT) | 1979-01-16 | — | — | US | disclosed |