Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | SCN1A | P35498 | 6/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 6/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 6/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11561313 | 1.00 | MEN1 (0.61) | MEN1KMT2ATDP1SCN1ASCN2A | |
| SCHEMBL991408 | 0.89 | MEN1 (0.63) | MEN1KMT2ATDP1SCN1ASCN2A | |
| SCHEMBL18013744 | 0.88 | TDP1 (0.73) | MEN1KMT2ATDP1TSHRLMNA | |
| SCHEMBL11852023 | 0.86 | MEN1 (0.56) | MEN1KMT2ATDP1SCN1ASCN2A | |
| SCHEMBL991809 | 0.86 | MEN1 (0.66) | MEN1KMT2ATDP1TSHRLMNA | |
| SCHEMBL11554831 | 0.84 | MEN1 (0.71) | MEN1KMT2ATDP1TSHRLMNA | |
| SCHEMBL11558044 | 0.84 | MEN1 (0.71) | MEN1KMT2ATDP1TSHRLMNA | |
| SCHEMBL992355 | 0.83 | MEN1 (0.66) | MEN1KMT2ATDP1TSHRLMNA | |
| SCHEMBL18256284 | 0.83 | MEN1 (0.66) | MEN1KMT2ATDP1TSHRLMNA | |
| SCHEMBL19821665 | 0.81 | MEN1 (0.66) | MEN1KMT2ATDP1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146623-A | SUBSTITUTED FUROIC ACIDS AND ESTERS | RICHARDSON-MERRELL INC. (US) | 1979-03-27 | — | — | US | disclosed |
| US-4110351-A | Hypolipidemic agents RO- or RS- substituted furoic acids, esters and salts | RICHARDSON-MERRELL INC. (US) | 1978-08-29 | — | — | US | disclosed |