Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11554831 | 1.00 | MEN1 (0.71) | MEN1KMT2ATDP1HDAC4HDAC6 | |
| SCHEMBL18013744 | 0.93 | TDP1 (0.73) | MEN1KMT2ATDP1ALDH1A1TSHR | |
| SCHEMBL19821665 | 0.87 | MEN1 (0.66) | MEN1KMT2ATDP1ALDH1A1TSHR | |
| SCHEMBL991809 | 0.87 | MEN1 (0.66) | MEN1KMT2ATDP1ALDH1A1TSHR | |
| SCHEMBL992355 | 0.87 | MEN1 (0.66) | MEN1KMT2ATDP1ALDH1A1TSHR | |
| SCHEMBL18256284 | 0.87 | MEN1 (0.66) | MEN1KMT2ATDP1HDAC4HDAC6 | |
| SCHEMBL11563597 | 0.87 | MEN1 (0.73) | MEN1KMT2ATDP1ALDH1A1TSHR | |
| SCHEMBL991850 | 0.87 | MEN1 (0.73) | MEN1KMT2ATDP1ALDH1A1TSHR | |
| SCHEMBL19821452 | 0.86 | MEN1 (0.64) | MEN1KMT2ATDP1ALDH1A1TSHR | |
| SCHEMBL11556689 | 0.85 | TDP1 (0.67) | MEN1KMT2ATDP1HDAC6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4110351-A | Hypolipidemic agents RO- or RS- substituted furoic acids, esters and salts | RICHARDSON-MERRELL INC. (US) | 1978-08-29 | — | — | US | claimed |
| US-4146623-A | SUBSTITUTED FUROIC ACIDS AND ESTERS | RICHARDSON-MERRELL INC. (US) | 1979-03-27 | — | — | US | disclosed |
| US-4110351-A | Hypolipidemic agents RO- or RS- substituted furoic acids, esters and salts | RICHARDSON-MERRELL INC. (US) | 1978-08-29 | — | — | US | disclosed |