Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL992355 | 0.94 | MEN1 (0.66) | TDP1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL11558044 | 0.93 | MEN1 (0.71) | TDP1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL11554831 | 0.93 | MEN1 (0.71) | TDP1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL18256284 | 0.92 | MEN1 (0.66) | TDP1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL991809 | 0.92 | MEN1 (0.66) | TDP1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL992244 | 0.91 | MEN1 (0.61) | TDP1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL991408 | 0.89 | MEN1 (0.63) | TDP1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL16268280 | 0.89 | ALDH1A1 (0.62) | TDP1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL1357375 | 0.89 | ALDH1A1 (0.62) | TDP1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL15422580 | 0.89 | ALDH1A1 (0.62) | TDP1MEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9975867-B2 | Synthetic process for preparing 2-furoic acid derivatives | DERMIRA INC. (US) | 2018-05-22 | — | — | US | disclosed |
| US-20180028487-A1 | DERMATOLOGICAL FORMULATIONS OF 2-(2-ETHOXY-2-OXOETHYL)(METHYL)AMINO-2-OXOETHYL 5-(TETRADECYLOXY)FURAN-2-CARBOXYLATE | DERMIRA, INC. | 2018-02-01 | — | — | US | disclosed |
| US-20160229825-A1 | SYNTHETIC PROCESS FOR PREPARING 2-FUROIC ACID DERIVATIVES | DERMIRA, INC. | 2016-08-11 | — | — | US | disclosed |
| US-20160229825-A1 | SYNTHETIC PROCESS FOR PREPARING 2-FUROIC ACID DERIVATIVES | DERMIRA, INC. | 2016-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180028487-A1 | DERMATOLOGICAL FORMULATIONS OF 2-(2-ETHOXY-2-OXOETHYL)(METHYL)AMINO-2-OXOETHYL 5-(TETRADECYLOXY)FURAN-2-CARBOXYLATE | CUTA, CYP1A2, DPM1 | TDP1 2071/4885MEN1 3030/4885KMT2A 339/4885 |
| US-20160229825-A1 | SYNTHETIC PROCESS FOR PREPARING 2-FUROIC ACID DERIVATIVES | ALAD, CYP4F2, CYP2F1 | TDP1 4047/4885MEN1 2178/4885KMT2A 1455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.