Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11556607 | 0.75 | CDK1 (0.54) | KDM4EPOLBCDK1IKBKBADORA2A | |
| SCHEMBL12283253 | 0.75 | CDK1 (0.35) | POLBCDK1IKBKBADORA2AADORA1 | |
| SCHEMBL12261690 | 0.75 | CDK1 (0.35) | POLBCDK1IKBKBADORA2AADORA1 | |
| SCHEMBL763786 | 0.72 | CDK1 (0.60) | LMNAALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL26976 | 0.68 | ADORA2A (0.61) | LMNAADORA2AADORA1 | |
| SCHEMBL29551511 | 0.64 | CDK1 (0.34) | POLBCDK1ADORA2AADORA1 | |
| SCHEMBL7617554 | 0.64 | CDK1 (0.37) | POLBCDK1ADORA2AADORA1 | |
| SCHEMBL12311046 | 0.64 | ADORA2A (0.46) | LMNAALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL1260282 | 0.64 | CDK1 (0.34) | POLBCDK1ADORA2AADORA1 | |
| SCHEMBL8272 | 0.64 | PDPK1 (0.61) | LMNAALDH1A1KDM4EGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147867-A | ANTITUMOR AGENTS | GOLOVCHINSKAYA ELENA S | 1979-04-03 | — | — | US | disclosed |
| US-4147867-A | ANTITUMOR AGENTS | GOLOVCHINSKAYA ELENA S | 1979-04-03 | — | — | US | disclosed |
| US-4122173-A | POLYETHYLENE COATING | GOLOVCHINSKAYA ELENA SEMENOVNA | 1978-10-24 | — | — | US | disclosed |
| US-4122173-A | POLYETHYLENE COATING | GOLOVCHINSKAYA ELENA SEMENOVNA | 1978-10-24 | — | — | US | disclosed |